1. Juliana Laudiceia Marques Soares

Provided is a connector suitable for securely infixing a catheter, electrode, hollow needle, probe, or other styliform device with its tip stabilized within a nontubular anatomical structure. Secure junctions between fluid lines and/or electrodes and tissue are essential for automatic controls and permanent nephrostomies and suprapubic cystostomies, for example, using synthetic materials. These can be made self-contained and fully implanted to treat one chronic condition, or represent but one module controlled as an axis or channel of control in an adaptive ambulatory hierarchical prosthetic disorder response system used to automatically coordinate the treatment of chronic comorbid disease. Such applications require prosthesis-to-native tissue junctions which are secure, immobile, unsusceptible to leaks or microbial intrusion, and require little if any maintenance. Connection for securely and least disruptively merging catheteric and native lumina is described in nonprovisional application Ser.

Juliana Laudiceia Marques Soares

14/121,365, entitled Ductus Side-entry Jackets and Prosthetic Disorder Response Systems, filed on 25 Aug. Now claimed novel as to warrant the issuance of Letters Patent is: 1. A tissue connector for apposition against bodily tissue comprising a platform cushioned beneath, said platform having means for securely and rigidly engaging said tissue thereby to fasten to said tissue therapeutic and/or diagnostic devices in working relation to said tissue. A tissue connector according to claim 1, wherein said means for securely and rigidly engaging said tissue comprises a plurality of rounded rotatable tissue-undercutting and anchoring needles and said therapeutic or diagnostic devices are interchangeably mounted to said platform, said devices selected from the group comprised of fluid delivery lines, electrical wires, an electromagnet, an aspiration line, an electrode, a cabled device such as an endoscope, excimer laser, alone or in combination with any of the others. A tissue connector according to claims 1 and 2, wherein at least one said fluid delivery line is dedicated to the maintenance of the junction between connector and tissue connected and the device selected from said group, and the tissue connected through delivery of medication selected from the group comprised of antimicrobials, anti-inflammatories, immunosuppressives, and anticoagulants.